Ocular and cardiovascular response to topical carteolol 2% and timolol 0.5% in healthy volunteers. |
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| Authors: | D. J. Brazier and S. E. Smith |
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| Affiliation: | Department of Clinical Pharmacology, St Thomas's Hospital Medical School (UMDS), London. |
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| Abstract: | Ocular and cardiovascular effects of carteolol 2%, timolol 0.5%, and dummy eyedrops have been measured in a single dose double-blind crossover study in six healthy volunteers. Both drugs lowered intraocular pressure and reduced exercise-induced tachycardia. Neither produced a significant change in resting heart rate or blood pressure. The two agents appear comparable as regards ocular hypotensive and cardiovascular effects. |
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