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Hesperidin protects against behavioral alterations and loss of dopaminergic neurons in 6-OHDA-lesioned mice: the role of mitochondrial dysfunction and apoptosis
Authors:Antunes  Michelle S.  Ladd  Fernando Vagner Lobo  Ladd   Aliny Antunes Barbosa Lobo  Moreira   Amanda Lopez  Boeira   Silvana Peterini  Cattelan Souza  Leandro
Affiliation:1.Laboratory of Pharmacological and Toxicological Evaluations Applied to Bioactive Molecules, Federal University of Pampa, Itaqui, RS, CEP 97650-000, Brazil
;2.Department of Morphology/Laboratory of Neuroanatom, Biosciences Center, Federal University of Rio Grande do Norte, Natal, RN, Brazil
;3.Laboratory of Stochastic Stereology and Chemical Anatomy, Department of Surgery, College of Veterinary Medicine and Animal Science, University of S?o Paulo, S?o Paulo, Brazil
;
Abstract:Metabolic Brain Disease - Hesperidin is a flavonoid glycoside that is frequently found in citrus fruits. Our group have demonstrated that hesperidin has neuroprotective effect in 6-hydroxydopamine...
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