呼吸机双水平气道正压通气治疗重叠综合征合并呼吸衰竭的疗效评估 |
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引用本文: | 王亮,孟静,杨超,郭贝贝,魏亚茹. 呼吸机双水平气道正压通气治疗重叠综合征合并呼吸衰竭的疗效评估[J]. 中国医学装备, 2021, 0(1): 90-94 |
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作者姓名: | 王亮 孟静 杨超 郭贝贝 魏亚茹 |
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作者单位: | 河北省胸科医院呼吸科;石家庄市第二医院妇产科 |
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基金项目: | 河北省科技厅科技计划(18277767D)“双水平正压通气在重叠综合征(OS)患者治疗中临床疗效分析”。 |
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摘 要: | 目的:评估呼吸机双水平气道正压通气(BiPAP)和持续气道正压通气(CPAP)在治疗重叠综合征(OS)合并呼吸衰竭的临床疗效及差异性.方法:选取在医院睡眠呼吸监测诊疗中心诊疗的120例OS患者,根据治疗中呼吸机通气方式不同将其分为观察组(70例)和对照组(50例).观察组采用BiPAP联合常规药物治疗,对照组采用CPA...
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关 键 词: | 双水平正压通气(BiPAP) 慢性阻塞性肺疾病(COPD) 阻塞性睡眠呼吸暂停综合征(OSAS) 重叠综合征(OS) 呼吸衰竭 疗效评估 |
The observation on curative effect of BiPAP of ventilator in treating OS with respiratory failure |
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Affiliation: | (Respiratory Department,Hebei Province Chest Hospital,Shijiazhuang 050041,China) |
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Abstract: | Objective:To observe the difference s of clinically curative effect of bi-level positive airway pressure(BiPAP)and continuous positive airway pressure(CPAP)in treating overlap syndrome(OS)with respiratory failure.Methods:A total of 120 patients with OS accepted treatment in hospital were selected,and they were divided into observation group(70 cases)and control group(50 cases)according to the different ventilation mode of ventilator.The observation group(70 cases)adopted BiPAP combined with conventional medicine treatment,and the control group(50 cases)adopted CPAP combined with conventional medicine treatment.The duration of positive pressure ventilation and the ratio of“converted to tracheal intubation ventilation”in the all ventilation of the two groups were recorded and compared.A series of indicators of arterial blood gas analysis included pH value,arterial partial pressure of oxygen(PaO2),partial pressure of carbon dioxide in artery(PaCO2),oxyhemoglobin saturation(SaO2),forced vital capacity(FVC)of pulmonary function,forced expiratory volume at the 1th second(FEV1),the ratio of FEV1 and FVC(FEV1/FVC),apnea hypopnea index(AHI),the total sleep time(TST)and the lowest arterial O2 saturation pre and post treatment between two groups were observed and compared.Results:Five cases(7.1%)converted to the treatment of tracheal intubation ventilation in observation group post treatment,and 10 cases converted to that in control group post treatment(x2=4.408,P<0.05).The ventilator use time and hospital stay in observation group were significantly lower than those in control group(t=7.328,t=3.168,P<0.05).After the treatment,the total sleep time,the lowest oxygen saturation and AHI in observation group were significantly better than those in control group(t=2.274,t=2.137,t=8.085,P<0.05).The PaO2 and SaO2 in observation group were significantly higher than those in control group,and PaCO2 of observation group was significantly lower than that of control group(t=2.676,t=1.998,t=2.215,P<0.05).Compared with the levels of FVC,FEV1,FEV1/FVC of two groups before treatment,those were increased significantly after treatment,and those of observation group were significantly higher than those of control group(t=3.918,t=2.339,t=2.196,P<0.05).Conclusion:For OS patients with respiratory failure,both BiPAP mode and CPAP mode can improve the lung function and sleep quality of patients at night,and enhance related indicators of pulmonary ventilation.But BiPAP mode can shorten the use time of ventilator and contribute to blood gas analysis and the recovery of lung function indicators. |
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Keywords: | Bi-level positive airway pressure(BiPAP) Chronic obstructive pulmonary disease(COPD) Obstructive sleep apnea syndrome(OSAS) Overlap syndrome(OS) Respiratory failure Efficacy assessment |
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