玻璃体腔内注射曲安奈德治疗严重糖尿病性黄斑水肿

目的评价玻璃体腔内注射曲安奈德治疗糖尿病性黄斑水肿的疗效和安全性。方法对26例严重糖尿病性黄斑水肿患者玻璃体腔内注射4mg曲安奈德治疗。结果随访观察6个月，最佳矫正视力均有不同程度改善，眼底荧光血管造影显示黄斑区荧光渗漏减少甚至部分患者无渗漏；光学相干断层扫描检查显示黄斑区视网膜厚度显著降低，黄斑水肿均减轻。治疗后第7d眼内压有不同程度升高，经局部滴降眼压药治疗1个月后眼压得到控制。术后发生假性眼内炎1例。结论曲安奈德治疗糖尿病性黄斑水肿安全有效。

Effects of triamcinolone acetonide treatment for diabetic macular edema

Objective To evaluate the therapeutic effects and security of intra-vitreous injection of triamcinlolne acetonied （TA） for diabetic rnacular edema. Methods 26 patients with diabetic macular edema were treated with intravitrous injection of 4mg TA. Results During 6 months follow-up, the visual acuity of all patients had improved in varying degrees. Fundus fluorescein angiography（FFA）showed a significant decrease in macular leakage, even no leakage in some patients. Optical coherence tomography（OCT）also showed a significant decrease in central macular thickness. Macular edema was improved in all patients, and the intraocular pressure increased after 7 days and was controlled in one month. Pseudo-ophthalmia was found in 1 patient. Conclusion TA is effective and safe for diabetic rnacular edema.