Cardiac resynchronization therapy in patients with minimally symptomatic heart failure

Cardiac resynchronization therapy improves mortality and heart failure symptoms in patients with sinus rhythm, depressed left ventricular ejection fraction, a wide QRS complex and moderate-to-severe heart failure symptoms. The results of recent trials suggest that in similar patients with minimal heart failure symptoms cardiac resynchronization therapy is associated with left ventricular reverse remodeling, and may prevent the progression of heart failure.