| 临床导向的创新中药研究 |
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| 引用本文： | 肖红斌,刘丹,刘艳秋,张良晓.临床导向的创新中药研究[J].世界科学技术-中医药现代化,2013,15(1):20-24. |
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| 作者姓名： | 肖红斌 刘丹 刘艳秋 张良晓 |
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| 作者单位： | 中国科学院大连化学物理研究所 大连 116023 |
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| 基金项目： | 国家自然科学基金重大研究计划面上项目（90709014）：糖尿病代谢谱与其中医证候的相关性研究，负责人：肖红斌。 |
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| 摘 要： | 继承传统中医药理论和中药整体调理、辨证施治治疗特色,发展成分明确、机理清楚、质量可控的创新中药是中药现代化的主要任务.在当前转化医学提出的国际化背景下,发挥传统中药丰富临床经验的优势,结合现代“组学”等整体研究的思路,探寻临床观察-实验验证-临床检验的转化医学研究模式,将为传统中药的继承和发展提供新思路,为创新中药的开发提供新方法.
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| 关 键 词： | 转化医学 创新中药 谱效学 代谢组学 |
| 收稿时间： | 2012/12/24 0:00:00 |
| 修稿时间： | 2013/2/19 0:00:00 |
Clinically-oriented Innovation of Chinese Materia Medica |
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| Xiao Hongbin,Liu Dan,Liu Yanqiu and Zhang Liangxiao.Clinically-oriented Innovation of Chinese Materia Medica[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2013,15(1):20-24. |
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| Authors: | Xiao Hongbin Liu Dan Liu Yanqiu and Zhang Liangxiao |
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| Institution: | Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China |
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| Abstract: | It is a key task in traditional Chinese medicine (TCM) modernization and internationalization to develop Chinese Materia Medica (CMM) with the clear component, interaction mechanism and controllable quality based on the inheritance of TCM theories and characteristics of systematic regulation & individual treatment according to TCM syndrome. With the upsurge of translational medicine, the novel methods of metabonomics and other-omics will be married with the plentiful TCM clinical experiences according to the regulation of translational medicine, i.e., from the clinical trial to laboratory research and back to clinical therapies for patients. Undoubtedly, this research mode of translational medicine will provide fresh inspiration for inheritance and development of traditional Chinese medicine. |
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| Keywords: | Translational medicine Chinese Materia Medica profile-effectiveness realationship metabonomics |
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