高渗盐液治疗急诊重度脑外伤并休克的临床观察

目的 研究急诊重度脑外伤合并休克的患者输注高渗盐液治疗的临床效果.方法 我院选择2010年8月-2012年8月间进行诊治的126例急诊重度脑外伤合并休克的患者,将其分为两组.观察组的64例患者在治疗早期即应用7.5%高渗盐液来降低颅内压,对照组的62例患者在治疗早期应用浓度为20%的甘露醇溶液来降低颅内压.结果 在降ICP方面,两组患者的临床效果基本一致,在维持降颅压的时间上,观察组明显优于对照组,差异显著,在维持MAP基本不变时,观察组的HR、CPP、UPD均优于对照组,差异显著,有统计学意义（P〈0.05）.结论 高渗盐液适合用于重度颅脑外伤合并创伤性休克的患者,值得在临床上推广使用.

Clinical observation of hypertonic saline in emergency patients with severe brain trauma and shock

Objective To study the clinical effect of emergency and severe cerebral infusion of hypertonic saline treatment in patients with traumatic shock. Methods 126 cases of emergency department of our hospital in August 2010 -2012 year in August for the diagnosis and treatment of severe brain injury patients complicated with shock, divided into two groups. 64 patients in observation group in the treatment of early application of 7.5% hypertonic saline solution to reduce intracranial pressure, 62 patients in the control group in the treatment of early application of concentration of mannitol to lower intracranial pressure 20%. Results in ICP, the clinical effect of two groups were basically the same, decreasing intracranial pressure time in maintenance, the observation group than the control group, significant difference, in the maintenance of MAP basically unchanged, the observation group HR, CPP, UPD were superior to the control group, the difference was significant, with statistical significance （P〈0.05）. Conclusion hypertonic saline solution suitable for patients with severe craniocerebral injury complicated with traumatic shock, worthy of promotion in clinical use.