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The prevalence of common CFTR mutations in Iranian infertile men with non-CAVD obstructive azoospermia by using ARMS PCR techniques
Authors:Kyumars Safinejad  Mojtaba Darbouy  Sayed Mahdi Kalantar  Sirus Zeinali  Reza Mirfakhraie  Leila Yadegar  Masoud Houshmand
Affiliation:(1) Fars Science and Research branch, Islamic Azad University, Shiraz, Iran;(2) Research & Clinical Centre for Infertility, Shahid Sadoughi Medical Sciences University Yazd, Yazd, Iran;(3) Department of Molecular Medicine, Pastor Institute of Iran, Tehran, Iran;(4) Department of Medical Genetics, Faculty of Medicine, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran;(5) Department of Biology, Faculty of Science, Payam Noor University (PNU), Tehran, Iran;(6) National Institute of Genetic Engineering and Biotechnology, Tehran, Iran;(7) Department of Genetic, Special Medical Center, Tehran, Iran
Abstract:

Purpose  

To evaluate five common cystic fibrosis trans-membrane conductance regulator (CFTR) mutations (ΔF508, G542X, R117H, W1282X and N1303K) in the Iranian infertile men with noncongenital absence of vas deferens (CAVD) obstructive azoospermia.
Keywords:Obstructive azoospermia   Common CFTR gene mutations   Non CAVD   Infertile men   ARMS PCR
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