SOX方案新辅助化疗联合腹腔镜辅助胃癌根治术的安全性及疗效评价

目的:探讨SOX方案新辅助化疗联合腹腔镜辅助胃癌根治术的安全性及疗效.方法:选取2017年1月—2019年1月期间我院收治的35例进展期胃癌患者为研究对象,根据患者及其家属意愿,将其分为腹腔镜辅助胃癌根治术治疗组(对照组,n=19)及SOX新辅助化疗联合腹腔镜辅助胃癌根治术治疗组(观察组,n=16).记录两组患者化疗相...

Safety and Efficacy of Sox Neoadjuvant Chemotherapy Combined with Laparoscopic Assisted Radical Gastrectomy for Gastric Cancer

Objective To investigate the safety and efficacy of Sox neoadjuvant chemotherapy combined with laparoscopic assisted radical gastrectomy for gastric cancer.Methods Thirty-five patients with advanced gastric cancer in our hospital were selected as the study objects from January 2017 to January 2019,according to the wishes of patients and their families.They were divided into two groups:laparoscopic assisted radical gastrectomy(control group,n=19)and SOX neoadjuvant chemotherapy combined with laparoscopic assisted radical gastrectomy(observation group,n=16).The incidence of chemotherapy-related adverse reactions was recorded in the observation group,and the operation related indexes,postoperative recovery,postoperative complications and 1-year survival rate were compared between the two groups.Results After neoadjuvant chemotherapy,there were 15 cases of chemotherapy-related adverse reactions in the observation group,the severity of which was mainly grade I and grade II.There was no significant difference between the two groups in operative time,intraoperative blood loss,intraoperative blood transfusion and intraoperative lymph node dissection(P>0.05).The radical resection rate of the observation group was higher than that of the control group(P<0.05).There was no significant difference between the two groups in the time of getting out of bed,anal exhaust and hospitalization(P>0.05).The incidence of incision infection,abdominal infection and hair coloring were not statistically significant in the two groups(P>0.05).The 1 year survival rate in the observation group was higher than that in the control group(93.75%vs 84.21%),but the difference was not statistically significant(P>0.05).Conclusion SOX neoadjuvant chemotherapy combined with laparoscopic assisted radical gastrectomy can improve the radical resection rate of advanced gastric cancer,which is a safe and feasible treatment.