独一味胶囊辅助经尿道微创手术治疗前列腺增生合并膀胱结石的临床效果

目的:研究独一味胶囊辅助经尿道微创手术治疗高龄高危患者前列腺增生(BPH)合并膀胱结石的临床效果。方法:选取我院2019年1月—2019年9月收治的高龄BPH合并膀胱结石患者180例,随机分为对照组和研究组各90例,两组均采用经尿道前列腺电切术(TURP)联合钬激光(HLL)碎石术进行治疗,研究组在手术治疗的基础上术前、术后口服独一味胶囊,0.9 g/d,比较两组的手术时间、术中出血量、膀胱冲洗时间、留管时间、术后住院时间、并发症例数、手术前后1个月最大尿流率、残余尿量、术前国际前列腺症状(IPSS)评分、生活质量(QOL)评分、梗阻评分。结果:研究组与对照组相比,术中出血量(67.2±6.6)mL vs(75.4±8.2)mL]、术后出血(4例vs 12例)、术后出血量(28.5±4.9)mL vs(35.4±5.7)mL]、术后1个月IPSS评分(6.84±1.3)vs(8.4±1.9)]、QOL评分(2.3±0.5)vs(3.5±0.7)]均显著较低,差异有统计学意义(P<0.05)。结论:在TURP联合HLL碎石术治疗高龄高危患者BPH合并膀胱结石的过程中,服用独一味胶囊可显著提高手术疗效。

Study of Compound Lamiophlomis Rotata Capsule Assisted Transurethral Surgery in the Treatment of Senile and High Risk BPH Complicated with Bladder Stones

Objective To study the effect of lamiophlomis rotata capsule assisted transurethral minimally invasive surgery in the treatment of prostatic hyperplasia with bladder stones for the elderly and high-risk patients.Methods 180 patients with BPH and bladder stone were randomly divided into two groups:control group and study group.The two groups were treated with TURP and HLL.The study group took lamiophlomis rotata capsule before and after operation,0.9g/day,three times a day,on the basis of hand operation.The results were as follows:operation time,intraoperative bleeding volume,bladder washing time,retention time,postoperative hospitalization time,number of complications,maximum urine flow rate before and after operation,residual urine volume,preoperative International Prostate Symptom Score(IPSS),quality of life score(QOL)and obstruction score.Results Compared with the control group,the bleeding volume(67.2±6.6ml)vs(75.4±8.2ml)],bleeding volume(4 vs 12),bleeding volume(28.5±4.9)ml vs(35.4±5.7)ml],IPSS score(6.84±1.3)vs(8.4±1.9)]and QOL score(2.3±0.5)vs(3.5±0.7)]in the study group were significantly lower than those in the control group(P<0.05).Conclusion In the course of TURP combined with HLL lithotripsy in the treatment of BPH with bladder stones for the elderly and high-risk patients,lamiophlomis rotata capsule could significantly improve the surgical treatment.