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C-反应蛋白在冠心病诊断中的价值与文献评价
引用本文:陈志晓,杨凤爱,张辉荣,伍绍东.C-反应蛋白在冠心病诊断中的价值与文献评价[J].实用医技杂志,2008,15(27):3653-3654.
作者姓名:陈志晓  杨凤爱  张辉荣  伍绍东
作者单位:1. 阳江市人民医院,广东,阳江,529500
2. 阳江市中西医结合医院,广东,阳江,529500
3. 中山大学附属第五医院,广东,珠海,519000
摘    要:目的:从循证医学的角度对C-反应蛋白诊断冠心病价值作文献评价。方法:参照诊断性试验的评价指标对文献的设计方案、研究对象的选择、参考值的确立、诊断试验的评价指标等进行评价。结果:在纳入的65篇文献中49篇说明了研究对象的来源;27篇与金标准进行了比较;只有1篇提及盲法,没有文章说明临界值的确定,没有文章说明诊断性指标(敏感度、特异度、似然比等)。结论:提示目前尚无临床证据表明C-反应蛋白作为冠心病的独立指标。

关 键 词:C反应蛋白  冠心病  循证医学  金标准  诊断试验

Evaluation of the Value of C-reactive Protein in Literature of Coronary Heart Disease based on Evidence-based Medicine
CHEN Zhi-xiao,YANG Feng-ai,ZHANG Hui-rong,WU Shao-dong.Evaluation of the Value of C-reactive Protein in Literature of Coronary Heart Disease based on Evidence-based Medicine[J].Journal of Practical Medical Techniques,2008,15(27):3653-3654.
Authors:CHEN Zhi-xiao  YANG Feng-ai  ZHANG Hui-rong  WU Shao-dong
Institution:CHEN Zhi-xiao1; YANG Feng-ai1; ZHANG Hui-rong2; WU Shao-dong3(1.Yangjiang People s Hospital; Yangjiang; Guangdong 529500; China; 2.Combing Sino-western Hospital of Yangjiang; Guangdong 529503; 3.The Fifth Affiliated Hospital of Sun Yat-sen University; Zhuhai; Guangdong 519000; China);
Abstract:Objective To evaluate the value of C-reactive in literatures of coronary heart disease based on evidence-based medicine.Methods The literatures were evaluated according to the evidence-based medicine principles.Main outcomes include design methods,sample screening establishment of control group,blind method,and criteria of diagnostic trials.Results In the 65 collected reports,there were 49 reports which had explained where the study objects come from,gold standard was adopted in 27 reports,blind method was ...
Keywords:C-reactive protein  Coronary heart disease  Evidence-based medicine  Gold standard  Diagnosis tests
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