解脲脲原体三年来药敏结果分析

目的:了解本地区解脲脲原体耐药状况,指导临床合理用药。方法:应用支原体微量培养及同步药敏试剂盒,检测解脲脲原体及其药敏分析。结果:792例NGU病人281例UU阳性,阳性率35.5%。美满霉素、交沙霉素、克拉霉素、司帕沙星四种抗生素敏感性高,不易产生耐药性,且三年耐药率变化不大;阿奇霉素三年间耐药率显著上升,由8.11%上升到22.86%。氧氟沙星、左氧氟沙星、罗红霉素耐药率较高。结论:临床治疗UU引起的非淋菌性尿道炎,本地区应推荐美满霉素、交沙霉素作为治疗解脲脲原体的首选药物。

Analysis of Ureaplasma Urealyticum Drug Susceptibility in Three Years

Objective: To acquier the information about the present resistance characteristics in ureaplasma urealyticum(UU) in our area and to instruct reasonable application of antibiotic clinically.Method: Seriea of mycoplasma microculture and sychronism drug-sensitivity test kits were used to measure the ureaplasma urealyticum and to analyze the drug-sensitivity.Result: Among 792 cases of nongonoccocal urethritis(NGU),UU positive were 281cases,Positive rate was 35.5%.The Minocycline,Josamycin,Clarithromycin Spafloxacin showed sensitive response in susceptility test,The resistant rate of Azithromycin increased to a high level,from 8.11% in 2002 to 22.86% in 2004.The resistant rate of Ofloxcin,Levofloxcin,Roxithromycin were a high level.Conclusion: The Minocycline,Josamycin are recommended to be the first choice to treat NGU in our area.