腹腔镜与开腹直肠癌根治术的近期疗效及安全性分析

目的探讨腹腔镜直肠癌根治术与开腹直肠癌根治术治疗直肠癌的近期疗效及安全性。方法回顾性分析2011年1月至2016年7月收治的直肠癌162例患者临床资料,按术式不同分为腹腔镜组82例和开腹组80例,对比两种术式的短期疗效及安全性。采用SPSS 20.0统计软件进行分析,术中、术后各种指标及住院总费用采用(x珋±s)表示,采用t检验;术后并发症发生率采用χ2检验,P0.05为差异有统计学意义。结果腹腔镜组患者的术中出血、首次排气时间、首次排便时间、进流食时间及住院天数要显著少于开腹组患者(P0.05),而手术费用要显著高于开腹组(P0.05);两组患者病理学指标差异无统计学意义(P0.05);术后腹腔镜组患者并发症发生率为19.5%(16/82),开腹组为13.8%(11/80),差异无统计学意义(P0.05)。结论与传统开腹手术相比,腹腔镜直肠癌根治术具有创伤小、恢复快等优点,疗效确切安全可靠,值得推广应用。

Short-term clinical outcome and safety of laparoscopic and open radical resection of rectal cancer

Objective To investigate and to compare the short-term clinical outcome and safety of laparoscopic and open radical resection of colorectal cancer.Methods Clinical data of 162 patients with colorectal cancer from January 2011 to July 2016 were analyzed retrospectivelyt, including 82 cases in laparoscopic group and 80 cases in open group.Statistical analysis were performed by using SPSS 20.0 software.Perioperative measurement data and total hospitalization expenses were expressed as mean±standard deviation(±s), and were examined by using t test.The postoperative complications were expressed as "%" and analyzed by Chi-square test.A P value <0.05 was considered as statistically significant difference.Results First exhaust time, defecation time, eating time and hospital stay in laparoscopic group were significantly less than those in open group, with significant difference (P<0.05).However, the surgery cost in laparoscopic group was significantly higher than that in open group, with significant difference (P<0.05).There were no significant difference of pathological results between two groups (P>0.05).The incidence of complications was 19.5% (16/82) in laparoscopic group and was 13.8% (11/80) in open group, with no significant difference (P>0.05).Conclusions Compared with traditional open surgery, laparoscopic rectal resection has advantages such as less trauma, quicker recovery and effective safety and reliability, which should be widely applied.