|
|||||
|
|
Incidence of human parvovirus B19 DNA detection in blood donors |
|
| Authors: | Yuko Yoto Tooru Kudoh Keiji Haseyama Nobuhiro Suzuki Takanori Oda Toshiaki Katoh Tsuneo Takahashi Sadami Sekiguchi Shunzo Chiba |
| Affiliation: | Department of Paediatrics, Sapporo Medical University School of Medicine, Chuo-ku, Sapporo, Japan;Hokkaido Red Cross Blood Centre, Nishi-ku, Sapporo, Japan |
| Abstract: | Summary. 1000 serum samples from blood donors were tested for human parvovirus B19 (B19) DNA by a nested PCR assay: six samples were positive for B19 DNA. The frequency was 1/167 (0-6%), considerably higher than previous surveys (0-004-0-03%). Five of the six samples were also positive for anti-B19 IgM, indicating an acute phase of infection. It is recommended to screen for B19 DNA in blood products to prevent transfusion mediated viral infection for those susceptible such as immunocompromised patients and pregnant women. |
| Keywords: | erythema infectiosum human parvovirus B19 donated blood immunocompromised host infection via transfusion |