超选择动脉溶栓治疗急性脑梗死

目的评价艾立通(r-tPA)治疗急性脑梗死的临床疗效.方法对26例急性脑梗死病人,经股动脉插管,用微导丝将微导管超选择送至血管闭塞部位,注入r-tPA行溶栓治疗,其中3例病人采用血管成形术(PTA),并注入罂粟碱扩张狭窄血管.结果颈内动脉闭塞8例中6例完全再通,2例部分再通.大脑中动脉闭塞14例中13例完全再通,部分再通1例.椎基底动脉闭塞4例中完全再通2例,部分再通2例.治疗后10天临床神经功能缺损评分(European Stroke Scale,ESS)较术前明显改善.结论早期超选择动脉溶栓是治疗急性脑梗死最有效的方法之一.

Superselected arterial chrombolysis for treatment of acute cerebral infarction

Objective To evaluated the clinical effect of r-TPA in treating acute cerebral irdarction Methods 26 cases with acute cerebral infarction was injected intra-arterial reteplase(r-TPA)for proximal occlusion via superselective catheterization through femoral artery,however,3 cases underwem mechanical angioplasty(PTA),and recieved morphine.Results Of 8 occulusion in internal carotid artery,6 complete restoration of blood flow,2 localize;of 4 ccculusion in basilar artery,2 complete,2 localize;of 14 occulusion in sylvian artery.13 conplete,1 localize.At 10 days after treatmemt,all of the cases had neurologic im- provement(reflected in European Stroke Scale,ESS).Conclusion Superselected arterial chrombolysis in early is one of most offective meaeure for the treayment of acute cerebeal infmarction.