| 兔脑缺血时体感诱发电位的改变及胞二磷胆碱作用的观察 |
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| 引用本文： | 郑健,刘祚周,张基谟,廖维宏. 兔脑缺血时体感诱发电位的改变及胞二磷胆碱作用的观察[J]. 第三军医大学学报, 1988, 0(3) |
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| 作者姓名： | 郑健 刘祚周 张基谟 廖维宏 |
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| 作者单位： | 第三军医大学生理学教研室(郑健，刘祚周，张基谟)，第三军医大学生理学教研室(廖维宏) |
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| 摘 要： | 本实验通过阻断兔双侧椎动脉和颈总动脉血流建成全脑缺血模型。观察到脑缺血时,SEPs各波发放潜伏时、峰潜时延长,波幅降低,直至消失。恢复脑血液供应后,SEPs各波潜伏时逐渐缩短,波幅增大,趋于脑缺血前水平。CDP-choline可明显促进缺血脑功能的恢复。
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| 关 键 词： | 脑缺血 诱发电位 躯体感觉-药物作用 胞苷二磷酸胆碱-药效学 |
Observation of the Somatosensory Evoked Potentials and the Effect of CDP-choline in Rabbit with Brain Ischemia |
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| Zheng Jian,et al. Observation of the Somatosensory Evoked Potentials and the Effect of CDP-choline in Rabbit with Brain Ischemia[J]. Acta Academiae Medicinae Militaris Tertiae, 1988, 0(3) |
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| Authors: | Zheng Jian et al |
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| Abstract: | Global ischemia model was produced in rabbit by occluding bothvertibral and common carotid arteries. During brain ischemia the onset and peaklatencies of SEPs gradually increased, the amplitudes became lower, till all wavesdisappeared. After reconstruction of brain blood flow the latencies decreased andthe amplitudes increased to the control level. CDP-choline improved the recoveryof SEPs caused by brain ischemia obviously. |
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| Keywords: | Cerebral ischemia Evoked potentials Somatossnsory/drug effecfs Cytidine diphosphate cholien/pharmacodynamics |
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