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Endovascular Treatment for Lower-extremity Arterial Thrombosis in a Patient with Congenital Afibrinogenemia and a History of Bleeding Complications |
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| Authors: | Daisuke Hiramatsu Yoshito Ogihara Takeshi Matsumoto Kei Sato Akihiro Takasaki Tairo Kurita Ryuji Okamoto Hideo Wada Kaoru Dohi |
| Affiliation: | 1.Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan; 2.Department of Transfusion Medicine and Cell Therapy, Mie University Hospital, Japan; 3.Department of General and Laboratory Medicine, Mie Prefectural General Medical Center, Japan; Associated Department with Mie Graduate School of Medicine, Japan |
| Abstract: | Congenital afibrinogenemia is a rare autosomal recessive blood disorder that accompanies thrombotic complications and is associated with bleeding tendency. The management of these opposing complications remains a challenge. Endovascular treatment (EVT) for peripheral arterial thrombosis has not been described in previous studies. A 57-year-old man with congenital afibrinogenemia developed back pain and left lower leg pain. The cause of the pain was confirmed to be renal infarction and lower extremity arterial thrombosis by Doppler ultrasound and contrast-enhanced computed tomography. He was treated with EVT for the lower extremity arterial thrombosis, leading to an excellent short-term improvement without bleeding. |
| Keywords: | congenital afibrinogenemia peripheral arterial thrombosis endovascular treatment bleeding |