| 肿瘤微环境和口腔癌相关成纤维细胞 |
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| 引用本文： | 孙鑫,何永文. 肿瘤微环境和口腔癌相关成纤维细胞[J]. 国际病理科学与临床杂志, 2009, 29(4): 357-360 |
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| 作者姓名： | 孙鑫 何永文 |
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| 作者单位： | 昆明医学院附属口腔医院,昆明,650031;昆明医学院附属口腔医院,昆明,650031 |
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| 基金项目： | 国家自然科学基金,教育部新世纪优秀人才支持计划项目(NCET-07-0388). This work was supported by the National Natural Science Foundation of China,the Program for New Century Excellent Talents in University of Ministry of Education of the Peope's Repulic of China |
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| 摘 要： | 肿瘤微环境是一个有其自身特点的系统,它有别于正常细胞和其周围组织形成的环境。癌相关成纤维细胞(carcinoma-associated fibroblasts,CAFs)是肿瘤微环境中最主要的宿主细胞。口腔肿瘤微环境中的成纤维细胞有别于口腔正常成纤维细胞,在口腔肿瘤的发生、发展及治疗中起着重要作用。
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| 关 键 词： | 肿瘤微环境 癌相关成纤维细胞 口腔癌 |
| 收稿时间： | 2009-06-07 |
| 修稿时间： | 2009-07-10 |
Tumor microenvironment and oral carcinoma-associated fibroblasts |
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| SUN Xin,HE Yongwen. Tumor microenvironment and oral carcinoma-associated fibroblasts[J]. Journal of International Pathology and Clinical Medicine, 2009, 29(4): 357-360 |
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| Authors: | SUN Xin HE Yongwen |
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| Affiliation: | Affiliated Stomatological Hospital of Kunming Medical College, Kunming 650031, China |
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| Abstract: | The tumor microenvironment is a system with different characteristics from the normal tissue microenvironment. Carcinoma-associated fibroblasts (CAFs) are the most important cells in tumor microenvironment. Characteristics of the fibroblasts in the oral cancer microenvironment are different from the normal fibroblast cells. The fibroblasts in the oral cancer microenvironment play an important role in cancerogenesis, development, and metastasis. |
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| Keywords: | tumor microenvironment carcinoma-associated fibroblasts oral cancer |
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