病毒性肝炎合并糖尿病预后与病毒因素的关系分析

目的:探讨病毒性肝炎合并糖尿病的预后及其影响因素。方法:回顾性分析502例患者的预后及其影响因素。结果:1)502例患者好转所占比例最高(76.89%),其次是痊愈(14.34%),总体预后良好。2)分性别预后情况与总体预后一致。男女组间预后情况比较无统计学意义(P=0.333)。3)年龄<20岁组和年龄>80岁组100%好转;另三组好转率(约75%)及痊愈率相近(约14%),20～40岁组死亡率最低(2.50%);60～80岁组死亡率最高(7.44%)。各年龄段组间预后比较无统计学意义(P=0.130)。4)急性肝炎组预后最好;慢性肝炎组、肝硬化组、重型肝炎组。痊愈率逐渐下降,未愈和死亡逐渐增多,尤其是重型肝炎组预后最差。不同临床类型组间预后比较有统计学意义(P=0.000)。5)无并发症组、1个并发症组、2个并发症组、3个及以上并发症组,痊愈率明显下降,未愈率及死亡率明显增加。不同并发症个数组间预后比较有统计学意义(P=0.000)。6)甲型肝炎组预后最好;重叠感染组、乙型肝炎组预后差。不同病毒型别组间预后比较有统计学意义(P=0.000)。结论:502例患者总体预后良好。乙型和重叠感染的重型肝炎及肝硬化患者顸后差一些,并发症个数越多预后越差,性别和年龄对疾病预后无明显影响。

Prognosis and its affecting factors of viral hepatitis combined with diabetes mellitus

Objective ： To analyze prognosis and its affecting factors of viral hepatitis combined with diabetes mellitus. Methods ： Retrospective analysis of hospital admitted 502 cases of viral hepatitis combined with diabetes mellitus from Jan 1st 2004 to Dec 31th 2010 prognosis and the connection between prognosis and the gender, age, viral type, viral hepatitis clinical type, count of complication. Resuhs： 1 ）The prognosis of 502 cases of viral hepatitis combined with diabetes mellitus prevalence of diabetes meUitus was good. Of them 14.34% were fully recovered. 76.89% were in effect. 2） The prognosis distribution of male group was similar with that of female group and total group. There was no significant deference in prognosis distribution between male group and female group （ P = 0.333）. 3） Age bellow 20 years old group and age above 80 years old group had the highest ra- tio of being in effect （ 100.00% ）. Not only ratio of recovery but also being in effect in other three group were similar each other. The lowest ratio of death was in age from 20 to 40 years old group. While The highest ratio of death was in age from 60 to 80 years old group. There was no significant deference in prognosis distribution between dissimilar age groups （ P = 0. 130）. 4） The acute hepatitis group had the best prognosis. Followed was chronic hepatitis group and cirrhosis group. Severe hepatitis group had the worst prognosis. There was significant deference in prognosis distribution between dissimilar clinical type groups （ P = 0.000）. 5） The prognosis was from bad to worst together with the number of complications increasing. There was significant deference in prognosis distribution between dissimilar count of complication groups （ P = 0.000） .6） The hepatitis A group had the best prognosis. Followed was hepatitis C group, hepatitis D group and hepatitis E group. The hepatitis germination viral group had bad prognosis. The hepatitis B group had the worst prognosis. There was significant deference in prognosis distribution between dissimilar viral type groups （ P = 0.000）. Conclusions：The prognosis of 502 cases of viral hepatitis combined with diabetes mellitus prevalence of diabetes mellitus was good. Severe hepatitis and cirrhosis patients with hepatitis B virus and germination virus infection had bad prognosis. The prognosis was from bad to worst together with the number of complications increasing. The gender and age have no effect on prognosis.