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Spasmogenic effect of Datura metel root extract on rat uterus and rectum smooth muscles |
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| Authors: | E. Prabhakar N. V. Nanda Kumar |
| Abstract: | The effect of Dautura metel leaf and root extracts, scopolamine and acetylcholine was studied on isolated smooth muscle preparations. Datura metel leaf extract and scopolamine showed antispasmodic effects, whereas Datura metel root extract and acetylcholine caused contracture in isolated rat uterus and rectum whole muscle. This suggests the presence of a spasmogenic factor in Datura metel root extract. |
| Keywords: | Datura metel uterus rectum acetylcholine scopolamine spasmogenic factor |