| Abstract: | The dried root of Rauvolfia vomitoria administered orally to 10 psychiatric patients at doses up to 800 mg/day, in divided doses, showed antipsychotic effects. The overall side effects were minimal, without serious incidence of extrapyramidal symptoms. Physical examination and laboratory parameters tend to correlate with the theory that Rauvolfia vomitoria accumulates in the plasma. The antipsychotic effects of Rauvolfia vomitoria were shown to be dose dependent when given three-times a day, with minimal side effects. |
