| 正交试验优化固本祛风颗粒提取工艺 |
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| 引用本文： | 俞冰,刘志承,李曙光,徐汉明,曹丽萍. 正交试验优化固本祛风颗粒提取工艺[J]. 中国药业, 2013, 22(14): 79-80 |
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| 作者姓名： | 俞冰 刘志承 李曙光 徐汉明 曹丽萍 |
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| 作者单位： | 1. 广东省深圳市中医院,广东深圳,518033
2. 广东省深圳市宝安中医院,广东深圳,518133 |
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| 基金项目： | 广东省医院药学研究基金资助项目,项目编号：2011A09 |
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| 摘 要： | 目的研究固本祛风颗粒的最佳提取工艺。方法采用正交试验设计,以黄芪甲苷含量、干膏得率为指标,考察水的用量、煎煮时间、煎煮次数3个因素对固本祛风颗粒提取效果的影响,优选提取工艺。结果最佳工艺条件为加8倍量水煎煮1 h,煎煮3次。结论该提取工艺合理可行,并能较好地保证制剂质量。
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| 关 键 词： | 固本祛风颗粒 黄芪甲苷 干膏得率 正交试验 提取工艺 |
Optimization of Extraction Technology for Gubenquefeng Granules with Orthogonal Test |
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| Yu Bing , Liu Zhicheng , Li Shuguang , Xu Hanming , Cao Liping. Optimization of Extraction Technology for Gubenquefeng Granules with Orthogonal Test[J]. China Pharmaceuticals, 2013, 22(14): 79-80 |
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| Authors: | Yu Bing Liu Zhicheng Li Shuguang Xu Hanming Cao Liping |
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| Affiliation: | 1.Shenzhen Municipal Hospital of Traditional Chinese Medicine,Shenzhen,Guangdong,China 518033;2.Baoan Hospital of Traditional Chinese Medicine,Shenzhen,Guangdong,China 518133) |
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| Abstract: | Objective To study the optimal extraction technology for Gubenquefeng Granules.Methods By using the orthogonal experimental design with the astragaloside content and the dry extract yield as the indexes,the influence of 3 factors of water amount,decocting time and decocting times on the extraction effect of Gubenquefeng Granules was investigated for optmizing the extraction technology.Results The optimized extracting technological conditions were with 8 times amount of water decocting for 3 times.Conclusion This extraction technology is reasonable and feasible,and can well guarantee the quality of this preparation. |
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| Keywords: | Gubenquefeng Granules astragaloside dry extract yiel orthogonal experiment extraction process |
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