痰热清注射液治疗肺炎51例

目的观察痰热清注射液治疗肺炎的临床疗效及安全性。方法选择医院2011年1月至2012年10月收治的肺炎患者102例,随机分成两组,每组各51例。对照组给予抗感染、抗病毒、营养支持、糖皮质激素、退热、机械通气、黏液溶解剂等常规对症治疗;治疗组在对照组基础上给予痰热清注射液0.3～0.5 mL/kg加入葡萄糖注射液500 mL中静脉滴注,每日1次,7 d为1个疗程。比较两组患者的临床疗效、临床症状及体征消失时间、住院时间及药品不良反应。结果治疗组总有效率为94.12%,明显高于对照组的84.31%(P<0.05),临床症状及体征消失时间、住院时间显著短于对照组(P<0.05),不良反应发生率显著少于对照组(P<0.05)。结论痰热清注射液治疗肺炎的疗效显著,可有效改善临床症状及体征,缩短住院时间,且不良反应小,值得临床推广。

Clinical Application of Tanreqing Injection in Treatment of Pneumonia in 51 Cases

Objective To observe the clinical efficacy and safety of Tanreqing Injection for the treatment of pneumonia. Methods 102 cases of pneumonia treated in our hospital from January 20ll to December 2012 were selected and randomly divided into two groups, 51 cases in each group. The control group was given anti- infective, anti- viral,nutritional support, glucocorticoid, antifebrile, mechanical ventilation, mucus dissolving agents, etc. conventional symptomatic treatment, while the treatment group was given Tanreqing Injection 0.3- 0. 5 mL/kg plus Glucose Injection 500 mL by intravenous drip based on the basis of the control group conventional symptomatic treatment, once a day, 7 d as a course of treatment. The clinical efficacy, disappearance time of clinical symptoms, hospitalization time and adverse reactions were compared between the two groups. Results The total effective rate was 94. 12% in the treatment group, which was significantly higher than 84.31% in the control group,the difference between them had statistical significance （P 〈 0.05）; the disappearance time of clinical symptoms and the hospitalization time in the treatment group were significantly shorter than those in the control group, the difference between the two groups was statistically significant （P 〈 0. 05）;the adverse reactions of treatment group were significantly less than those of the control group, the difference had statistical significance （P 〈 0. 05）. Conclusion Tanre- qing Injection in the treatment of pneumonia has significant effect,which can effectively improve the clinical symptoms and shorten the duration of hospitalization with less adverse reactions,and is worth being clinically promoted.