Investigation of the Anti-Snake Venom Activity of Schumanniophyton magnificum |
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| Authors: | Houghton P J Harvey A L |
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| Affiliation: | Pharmacognosy Research Laboratories, Chelsea Department of Pharmacy, King's College London (KQC), Manresa Rd, London SW3 6LX, U.K. |
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| Abstract: | Polar fractions of the methanolic extracts of the stem- and root-barks of SCHUMANNIOPHYTON MAGNIFICUM (Rubiaceae) reduced the effects of cobra venom cardiotoxin in the chick biventer cervicis nerve-muscle preparation IN VITRO. No activity was observed against a curaremimetic neurotoxin from cobra venom. Further fractionation of the extracts showed that the activity was not due to alkaloidal components, but the active substances could not be identified or isolated. |
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