未确定型结肠炎的特征分析

目的通过对未确定型结肠炎（indeterminate colitis，IC）患者的临床特点的分析，加深对该型结肠炎的认识。方法对2000年1月至2005年3月期间住院病历中符合炎症性肠病的217例患者的特点进行回顾性分析。结果未确定型结肠炎22例（10．2％），首发症状为腹泻54．5％，血便54．5％，腹痛31．8％，发热27．3％，有肠外表现59．1％，全结肠病变63．6％，回肠病变36．4％，节段型22．7％，直肠赦免50％，使用免疫抑制剂18．2％，手术31．8％。克罗恩病共60例，首发症状为腹痛76．7％，腹泻33．3％，发热25．0％，血便8．3％，有肠外表现38．3％，全结肠病变18．3％，节段型81．7％，回肠病变58．3％，使用免疫抑制剂11．7％，手术88．3％。溃疡性结肠炎135例，首发症状为脓血便78．5％，腹泻54．8％，腹痛29．6％，发热3．7％，有肠外表现18．5％，全结肠病变56．3％，节段型2．2％，回肠病变3．7％，使用免疫抑制剂的12．6％，手术6．7％。结论与克罗恩病及溃疡性结肠炎相比较，未确定型结肠炎有一些自己的特点，有可能是一个独立病变。

Analysis of the Characteristics of Indeterminate Colitis

Objective Through the analysis of the clinical characteristics of a group of IC patients,to gain a further recognition of IC. Methods Two hundred and seventeen in-patients qualified for IBD admitted from Jan.2000 to Mar.2005,were collected and analyzed retrospectively.Results There were 22 IC cases(10.2%),of which the commonest initial manifestations included diarrhea 54.5%,bloody stool 54.5% ,abdominal pain 31.8%,fever 27.3%. The other entities were as follows: extra-intestinal manifestations 59.1%,pancolic lesions 63.6%,ileum involvement 36.4%,segmental 22.7%,rectal sparing 50.0%. Eighteen point two percent and 31.8% received immunosuppressant and operation separately. There were 60 confirmed CD cases(27.6%),of which the commonest initial manifestations included abdominal pain 76.7%,diarrhea 33.3%,fever 25.0%,bloody stool 8.3%. Other entities were as follows: extra-intestinal manifestations 38.3%,pancolic lesions 18.3%,segmental 81.7%,ileum involvement 58.3%,11.7% and 88.3% of them received immunosuppressant and operations separately. UC was the most,altogether 135 cases(62.2%),of which the commonest initial manifestations included bloody stools 78.5%,diarrhea 54.8%,abdominal pain 29.6%,fever 3.7%. The other entities were as follows: extra-intestinal manifestations 18.5%,pancolic lesions 56.3%,segmental 2.2%,ileum involvement 3.7%. 12.6% and 6.7% of them received immunosuppressant and operations separately. Conclusion Compared with CD and UC,IC indeed has some unique characteristics. It may be a separate entity,or a subtype of IBD.