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Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria |
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| Authors: | Gentle Sunder Shrestha Bishesh Sharma Poudyal Gopal Sedain Khandokar Imran Mahmud Niranja Acharya |
| Affiliation: | From: Department of Anaesthesiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal;1.Department of Internal Medicine, Civil Service Hospital, Kathmandu, Nepal;2.Department of General Surgery, Neurosurgery Unit, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal;3.Department of Internal Medicine, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, England |
| Abstract: | Cerebral venous thrombosis (CVT) is an uncommon cause of stroke. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare type of hemolytic anemia, frequently associated with thrombophilia. PNH may rarely present with CVT. Approximately, one-third of the patients with CVT develop cerebral hemorrhage. Here, we present a rare combination of CVT presenting with intracerebral hemorrhage in a patient with PNH. High index of suspicion is needed to avoid misdiagnosis. Patient was successfully managed with anticoagulation therapy. |
| Keywords: | Cerebral venous thrombosis intracerebral hemorrhage paroxysmal nocturnal hemoglobinuria |