甲型肝炎病毒合并戊型肝炎病毒感染136例临床分析

目的　观察分析甲型病毒性肝炎合并戊型病毒性肝炎 (甲肝合并戊肝 )的临床表现及转归预后。方法　采用ELISA方法检测患者抗HAV IgM和抗HEV。结果　甲肝合并戊肝出现发热和肝大的病例分别占 6 9.85 %和 6 3 .97% ,显著高于单纯甲型病毒性肝炎 (甲肝 )的 3 7.0 0 %和 3 5 .43 %。甲肝合并戊肝发病的平均年龄为 3 1.42± 11.2 1岁 ,显著高于甲肝的 2 3 .2 1± 9.2 3岁。结论　甲肝合并戊肝也是与甲肝类似的自限性、急性、黄疸型肝炎 ,但甲肝合并戊肝具有发病以中青年为主 ,发病年龄较甲肝偏大、发热和肝大发生率高、黄疸时间较长的特点。

The Clinical Analysis of 136 Cases with Co-infection of Hepatitis A Virus and Hepatitis E Virus

Objective To investigate the clinical course and prognosis of coinfection of hepatitis A and E.Method Anti HAV IgM and Anti HEV were detected by ELISA.Results The percent of patients with Hepatitis A and E who had fever and hepatomegalia is 69.85% and 63.97% respectively.It is significantly higher than single Hepatitis A,which were 37% and 35.43% respectively.The mean age of Hepatitis A and E,which is 31.42±11.21 years old,is also significantly higher than single Hepatitis A,which is 23.21±9.23 years old.Conclusions Hepatitis A and E is a self limiting,acute,icteric hepatitis similar to Hepatitis A.But by comparing to single Hepatitis A,Hepatitis A and E has the following characteristic:the older mean age,higher percent of patients who had fever and hepatomegalia,and the longer icteric course.