Efficacy And Safety Of Oral Sildenafil In Men With Erectile Dysfunction And Spinal Cord Injury |
| |
| Authors: | William H Gans Stanley Zaslau Scott Wheeler Giuseppe Galea jonathan M Vapnek |
| |
| Institution: | 1. Department of UrologyMount Sinai Medical Center, New York,;2. Department of UrologyBronx Veterans Affairs Hospital, Bronx, New York;3. Department of UrologyMount Sinai Medical Center, New York,;4. Department of UrologyBronx Veterans Affairs Hospital, Bronx, New York |
| |
| Abstract: | AbstractObjective: To assess the efficacy of sildenafil in men with spinal cord injury (SCI) and erectile dysfunction (ED).Methods: Seventeen men with SCI were selected from February to September 1998 for sildenafil treatment of ED. The initial dose of 25-mg was increased by 25-mg increments as needed. Patients underwent baseline physical examination and answered questions from the abridged International Index of Erectile Function before and during therapy.Results:Sixteen patients tolerated therapy; 1 developed hypotension and dis continued therapy. There was significant improvement in erectile function (P < .05) after 5.3 ± 2.2 months when compared with baseline or previous therapies (P < .05). Of the 17 patients,94% recommended sildenafil to others. Six of these16 patients were available for long-term follow-up. There was further significant improvement in quality of erection (P < .05), but no change in satisfaction.Conclusion:Sildenafil is effective and well tolerated in men with SCI and ED. |
| |
| Keywords: | Erectile dysfunction Spinal cord injury Sildenafil |
|
|
