| ConA对红细胞膜力学性质的影响 |
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| 引用本文： | 施岩,王乃康,孙大公,马维原,宋立川,杨跃平,吕智红,高铁,文宗曜.ConA对红细胞膜力学性质的影响[J].中国血液流变学杂志,1996(1). |
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| 作者姓名： | 施岩 王乃康 孙大公 马维原 宋立川 杨跃平 吕智红 高铁 文宗曜 |
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| 摘 要： | 本文研究了伴刀豆蛋白ＣｏｎＡ（Ｃｏｎｃａｎａｖａｌｉｎ Ａ）以受体配体的作用方 式对红细胞膜力学性质的影响，结果显示出：（１）经ＣｏｎＡ处理后的血影红细胞膜 （ｒｅｓｅａｌ ｇｏａｓｔ）蛋白构象发生改变，蛋白运动性下降；（２）红细胞变形恢复半时间缩 短．表明ＣｏｎＡ作用后的红细胞膜切变弹性模量可能增大；（３）红细胞机械脆性随 ＣｏｎＡ浓度呈上升趋势，说明膜稳定性受到影响；（４）红细咆膜脂流动性下降．
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| 关 键 词： | 红细胞膜 ConA 变形恢复 Band3 |
THE EFFECTS OF CONA ON RBC MEMBRANE MECHANICAL PROPERTIES |
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| Yen Shi,Naikang Wang,Dagong Sun,Eeiyuan Ma,Lichuan Song,Yueping Yang,Zhihong Lu and Zong - yao Wen.THE EFFECTS OF CONA ON RBC MEMBRANE MECHANICAL PROPERTIES[J].Chinese Journal of Hemorheology,1996(1). |
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| Authors: | Yen Shi Naikang Wang Dagong Sun Eeiyuan Ma Lichuan Song Yueping Yang Zhihong Lu and Zong - yao Wen |
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| Abstract: | The aim of this paper is to study the effects of ConA on RBC membrane mechanical properties. The results suggest: (1)The recovery time of RBC deformation deformation with ConA concentration; (2)The mechanical fragility of RBC membrane incease; (3)The conformation of RBC membrane proteins was altered after the treatment with ConA; (4) Both the membrane proteins and membrane lipid fluidity were reduced. |
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| Keywords: | RBC membrane ConA Deformation recovery Band 3 |
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