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莫西沙星治疗老年患者社区获得性肺炎的疗效
引用本文:吴群,吴冰.莫西沙星治疗老年患者社区获得性肺炎的疗效[J].海峡药学,2010,22(9):98-100.
作者姓名:吴群  吴冰
作者单位:福建省立医院干部特诊二科,福州,350001
摘    要:目的观察莫西沙星治疗老年患者社区获得性肺炎(CAP)的疗效及安全性。方法选择本院老年患者80例,随机分成莫西沙星组(实验组)40例和头孢曲松联合左氧氟沙星组(对照组)40例。结果实验组总有效率95%、对照组总有效率77.5%,两组比较有统计学差异(P〈0.05)。实验组的不良反应发生率7.5%,对照组的不良反应发生率10.0%,两组比较差异无统计学意义(P〉0.05)。结论莫西沙星治疗老年CAP安全、有效。

关 键 词:莫西沙星  社区获得性肺炎(CAP)  老年患者

Controlled clinical trials of moxifloxacin in old patients with community-acquired pneumonia
WU Qun,WU Bing.Controlled clinical trials of moxifloxacin in old patients with community-acquired pneumonia[J].Strait Pharmaceutical Journal,2010,22(9):98-100.
Authors:WU Qun  WU Bing
Institution:WU Qun,WU Bing
Abstract:OBJECTIVE To evaluate the efficiency and safety of moxifloxacin in old patients with community-acquired pneumonia(CAP).METHODS Aprospective design was conducted.80 old patients with CAP were randomly divided into trial group and control group.The 40 trial group members were treated with moxifloxacin.In the control group,40 patients were treated with levofloxacin and ceftriaxone sodium.Statistical difference was analyzedinterms effectiveness,side effects and the comparisons were made between the groups.RESULTS After treatment,the total cured rate for the trail group was 95%,while for the control group it was 77.5%;P0.05.The adverse drug reaction rates were evaluated in 80 patients,showing the rates were 7.5% and 10% respectively with no significant statistical differences(P0.05).CONCLUSION Moxifloxacin is effective and safe in the treatment of old patients with CAP.
Keywords:Moxifloxacin  Community-acquired pneumonia(CAP)  Old patients
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