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Effect of histamine in sinus node arrested with reserpine
Authors:Witold Tuganowski  Grzegorz Budziński  Antoni Furmańczyk  Jerzy Sałabun
Affiliation:(1) Department of Physiology, Silesian Medical School, 41-808 Zabrze, Poland
Abstract:Summary Histamine restored spontaneous activity in the isolated rabbit sinus node arrested with reserpine. This fact suggests that catecholamines are not the unique activators of adenylate cyclase required for cardiac pacemaking, and may be replaced by histamine.
Keywords:Sinus node  Spontaneous activity  Histamine
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