我院209例药品不良反应报告分析

目的：分析我院药品不良反应（ADR）发生的特点和一般规律，促进临床合理用药。方法：采用回顾性方法，对我院2008年全年上报的209份ADR报告，按患者年龄、性别、给药途径、引发ADR的药品种类、涉及器官或系统及临床表现等进行统计、分析。结果：静脉给药较其他途径更易发生ADR（占77．99％）；抗感染药引发ADR的比例最高（66．99％），其次为中药制剂；头孢菌素类是引发ADR的主要抗感染药（59例，占42．14％），其中又以头孢匹胺为首。ADR的临床表现以皮疹、瘙痒等皮肤及附件损害为主，其次为消化系统及神经系统损害。结论：应强化ADR监测意识，完善相关报告分析制度，确保临床安全、有效、合理用药。

Analysis of 209 Reports of Adverse Drug Reactions in our Hospital

Objective:To analyze the characteristics and the regularity of adverse drug reactions in our hospital so as to promote rational drug use in the clinic.Method:209 ADR cases reported in our hospital in 2008 were analyzed with a retrospective analysis method,the data were statistically analyzed in terms of patients' age,sex,route of administration, drug categories inducing ADR,organs or systems involved and clinical manifestations.Result:Compared with other routes of administration,the intravenous injection wa...