胰腺浆液性囊腺瘤临床病理学分析

目的:探讨胰腺浆液性囊腺瘤的临床病理学特征。方法:对6例胰腺浆液性囊腺瘤进行临床病理资料回顾性分析,并复习相关文献。结果:6例胰腺浆液性囊腺瘤中,平均年龄52.6岁,男:女为1∶1,其中2例位于胰头部,4例位于胰体尾。临床表现均为胰腺囊性占位。本组6例均行手术治疗,其中微囊型3例、寡囊型2例、囊实型1例。组织学上,囊壁内衬扁平或立方上皮,胞质透亮,核圆形、卵圆形,大小一致,无明显核异型和核分裂象。6例肿瘤细胞均表达EMA、CK7、CK19阳性,且PAS阳性。4例患者随访时间4个月至2年不等,未发现肿瘤复发或转移,2例术后痊愈,出院失访。结论:胰腺浆液性囊腺瘤是一种良性肿瘤,术前确诊率较低,手术切除后预后好。

Serous cystadenoma of the pancreas: report of 6 cases and review of literatures

Objective:To study the clinicopathological features of serous cystadenoma of the pancreas(SCAP).Methods: Clinical data and pathologic findings of 6 cases of SCAP were analyzed,of which 4 had been follow-up.Results: Of 6 cases 3 were female and 3 were male,with an average age of 52.6 years.Clinical symptoms were found in 4 cases,and in 2 cases SCAP located in head of the pancreas and 4 cases in body and tail.All tumors were cystic,lined with flattened or cuboidal epithelial cells that had clear cytoplasm.According to the criteria of cystic size,3 were microcystic adenoma and 2 were oligocystic adenoma and one was cystic solid adenoma.In all cases,PAS of epithelial cells was positive.All 6 cases showed positive staining for EMA,CK7 and CK19,but most cases were negative for PASD and Ki67 were positive in one case.Recurrence or metastasis was not found in 4 patients followed-up for 4 months to 2 years.Conclusion: SCAP is seen preferably in elderly women,and most of them located in head of the pancreas,and nearly 2/3 patients had clinical symptoms.SCAP is originated from pancreatic ductal epithelial cell,and is a benign tumor with good prognosis.