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| 低强度He-Ne激光照射对大鼠肝GSH-PX活性、SOD活性及MDA含量的影响 | |
| 引用本文： | 崔芳,任雨笙,谢光柏,李玲,牟翔.低强度He-Ne激光照射对大鼠肝GSH-PX活性、SOD活性及MDA含量的影响[J].中国激光医学杂志,2003,12(3):161-163. |
| 作者姓名： | 崔芳 任雨笙 谢光柏 李玲 牟翔 |
| 作者单位： | 1. 第二军医大学长征医院理疗科,上海市,200003 2. 第二军医大学长征医院心内科 3. 第四军医大学西京医院理疗科 |
| 摘 要： | 目的观察不同能量密度的He-Ne激光照射大鼠肝区后,大鼠肝GSH-PX活性、SOD活性及MDA含量的变化,以探讨低强度He-Ne激光照射对肝组织活性氧自由基和与之相关酶的影响。方法分别用能量密度为2.98、5.97和8.96J/cm2的He-Ne激光照射大鼠肝区,每日照射1次,共照射10次。照射10次后观察大鼠肝组织中GSH-PX活性、SOD活性及MDA含量的变化,并与对照组进行对比。结果He-Ne激光照射组大鼠肝组织中GSH-PX活性、SOD活性较对照组均有不同程度增高,MDA含量有不同程度降低。尤以5.97J/cm2和8.96J/cm2最显著(P<0.05或P<0.01)。结论He-Ne激光照射可以增强肝组织清除活性氧自由基的能力,减轻自由基对组织细胞的损害。 |
| 关 键 词： | 低强度He-Ne激光照射 大鼠 肝 GSH-PX活性 SOD活性 MDA含量 谷胱甘肽过氧化物酶 超氧化物歧化酶 丙二醛 活性氧自由基 |
| 文章编号： | 1003-9430(2003)03-0161-03 |
| 收稿时间： | 2002/8/6 |
| 修稿时间： | 2002年8月6日 |
Effects of Low Density He-Ne Laser Irradiation on Glutathione Peroxidase and Superoxide Dismutase Activities and Malondialdehyde Contents of Liver in Rats |
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| CUI Fang ,REN Yu - sheng ,XIE Guang -bo ,LI Lin ,MU Xiang.Effects of Low Density He-Ne Laser Irradiation on Glutathione Peroxidase and Superoxide Dismutase Activities and Malondialdehyde Contents of Liver in Rats[J].Chinese Journal of Laser Medicine & Surgery,2003,12(3):161-163. | |
| Authors: | CUI Fang REN Yu - sheng XIE Guang -bo LI Lin MU Xiang |
| Institution: | CUI Fang 1,REN Yu - sheng 2,XIE Guang -bo 1,LI Lin 3,MU Xiang 3 1.Department of Physiotherapy&Rehabilitation,the Second Military Medical University,Shanghai200003,China2.Department of Cardiology,the Second Military MedicalUniversity3.Department of Physiotherapy&Rehabilitation,the Fourth Military Medical University |
| Abstract: | Objective To investigate the effects of He - Ne laser irradiation on the liver region of rats for changes in glutathione peroxidase(GSH - PX)and superoxide dismutase(SOD)activities and malondialdehyde(MDA)contents in liver.Methods He - Ne laser with energy density of2.98J /cm 2 ,5.97J /cm 2 and8.96J /cm 2 was employed for irradiation at the liver region of rats,once per day for10times.The changes in GSH - PX and SOD activities and MDA contents in liver were observed.Results It was found that the activity of GSH - PX and SOD in liver tissues of rats markedly rose,while the MDA contents noticeably declined.The effects were most remarkable in5.97J /cm 2 and8.96J /cm 2 groups(P<0.05,P<0.01).Conclusions The results suggest that He - Ne laser irradiation enhance the ability of antioxidation in liver tissues. |
| Keywords: | Laser Rat Glutathione peroxidase Superoxide dismutase Malondialdehyde |
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