| 胸腺切除术治疗重症肌无力的细胞免疫学机制 |
| |
| 引用本文： | 龚太乾,蒋耀光,王如文. 胸腺切除术治疗重症肌无力的细胞免疫学机制[J]. 免疫学杂志, 2002, 18(Z1): 221-223 |
| |
| 作者姓名： | 龚太乾 蒋耀光 王如文 |
| |
| 作者单位： | 第三军医大学第三附属医院全军胸外科中心,重庆,400042 |
| |
| 摘 要： | 胸腺切除术是治疗重症肌无力的主要方法之一.75%的重症肌无力患者伴有胸腺异常,增生胸腺存在AChR特异反应性T、B细胞,胸腺瘤中存在着T细胞的分化,有乙酰胆碱受体抗体(AChRAb)滴度升高.Tx可能去除了胸腺中导致B细胞活化的TH细胞,其相关的细胞因子也逐步下调,AChRAb逐步减少,最终MG的症状缓解.
|
| 关 键 词： | 胸腺切除术 重症肌无力 免疫学 |
| 文章编号： | 1000-8861(2002)03(S)-0221-03 |
| 修稿时间： | 2002-04-08 |
Cellular immunology of thymectomy for myasthenia gravis |
| |
| GONG Tai qian. Cellular immunology of thymectomy for myasthenia gravis[J]. Immunological Journal, 2002, 18(Z1): 221-223 |
| |
| Authors: | GONG Tai qian |
| |
| Abstract: | Thymectomy is one of the main methods in the management of myasthenia gravis. 75%of patients with myasthenia gravis have disorders in their thymus glands. There are specific response of T and B cells to AChR in hyperplasia thymus and differentiation of T cells with higher titer of AChRAb in thymoma. Thymectomy probably deletes helper T cells in thymus which activate B cells, cytokines associated with helper T cells .Titer of AChRAb drops. The symptom of myasthenia gravis remit. |
| |
| Keywords: | thymectomy myasthenia gravis immunology |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
