| 高血压脑出血患者IL-2、sIL-2R表达意义的研究 |
| |
| 引用本文： | 秋楠,党小军,张越林,缪星宇,许彦钢,王继军,杨军.高血压脑出血患者IL-2、sIL-2R表达意义的研究[J].现代检验医学杂志,2005,20(4):21-22. |
| |
| 作者姓名： | 秋楠 党小军 张越林 缪星宇 许彦钢 王继军 杨军 |
| |
| 作者单位： | 1. 陕西省人民医院神经外科,陕西,西安,710068
2. 陕西省人民医院检验科,陕西,西安,710068 |
| |
| 基金项目： | 陕西省科学技术研究发展计划项目(项目编号:2004K14-G9) |
| |
| 摘 要： | 目的研究高血压脑出血患者外周血中白细胞介素2(IL-2)、可溶性白细胞介素2受体(sIL-2R)表达的变化规律,探讨其间相互关系及临床意义。方法采用酶联免疫吸附法(ELISA)测定患者IL-2、sIL-2R的含量。结果高血压脑出血组IL-2含量(pg/ml)为67.76±32.62,与健康对照组(127.15±57.05)相比明显降低(P<0.01),sIL-2R含量(pg/ml)为96.91±50.14,与健康对照组(92.11±34.1)相比则明显升高(P<0.05)。结论高血压脑出血患者出现免疫功能低下,临床检测患者IL-2、sIL-2R含量在高血压脑出血的发生、发展、治疗、转归及预后方面具有重要的临床指导意义。
|
| 关 键 词： | 高血压脑出血 IL-2 sIL-2R |
| 文章编号： | 1671-7414(2005)04-021-02 |
| 修稿时间： | 2005年6月13日 |
Study on Alteration of IL-2,sIL-2R in Patients with Hypertensive Cerebral Hemorrhage |
| |
| QIU Nan,DANG Xiao-jun,ZHANG Yue-lin,MIAO Xing-yu,XU Yan-gang,WANG Ji-jun,YANG Jun.Study on Alteration of IL-2,sIL-2R in Patients with Hypertensive Cerebral Hemorrhage[J].Journal of Modern Laboratory Medicine,2005,20(4):21-22. |
| |
| Authors: | QIU Nan DANG Xiao-jun ZHANG Yue-lin MIAO Xing-yu XU Yan-gang WANG Ji-jun YANG Jun |
| |
| Abstract: | Objective To study the presence of interleukin - 2(IL-2),soluble interleukin-2 receptor(sIL-2) in the patients with hypertensi ve cerebral hemorrhage.To explore the relationship between them and the clinical significance.Methods Enzyme linked immunosorbent assay ( ELISA) was used to determine the content of IL-2 and sIL-2R.Results The content of IL-2 in the group with hypertensive cerebral hemorr hage was significantly lower than that in the control group (P<0.01),and t he content of sIL-2R increased.Conclusion The decrease o f immune function was observed in the patients with hypertensive cerebral hemorr hage.The determination of the content of IL-2 and sIL-2R has important clinica l guiding significance in the occurrence,development,treatment,outcome and progn osis of the hypertensive cerebral hemorrhage. |
| |
| Keywords: | hypertensive cerebral hemorrhage IL-2 sIL-2R |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
