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苏州地区小儿侵袭性肺炎链球菌耐药特征分析
引用本文:项龙,谢敏慧,柏振江,李莺. 苏州地区小儿侵袭性肺炎链球菌耐药特征分析[J]. 右江民族医学院学报, 2011, 33(5): 617-620. DOI: 10.3969/j.issn.1001-5817.2011.05.006
作者姓名:项龙  谢敏慧  柏振江  李莺
作者单位:苏州大学附属儿童医院重症监护室,江苏苏州,215003
摘    要:目的调查苏州地区小儿侵袭性肺炎链球菌(Streptococcus pneumoniae,SP)感染的现状及耐药特点,为预防和临床治疗提供依据。方法将有明确侵袭性SP感染患儿35例(41份标本)的临床特征及药敏试验进行分析。根据菌株耐药性分为青霉素敏感组(PSSP组)和青霉素不敏感组(PNSP组),分别比较两组菌株对抗生素的耐药性差异。结果 35例患儿中,男女比例1∶0.8,5岁以下占85.71%(30/35),脓毒症占74.29%(26/35),化脓性脑炎占31.43%(11/35),对青霉素的耐药率为48.78%(20/41),对万古霉素的耐药率为0(0/41)。青霉素不敏感组对SMZ、四环素的耐药性高于青霉素敏感组(P<0.05)。结论苏州地区小儿侵袭性SP病感染多见于5岁以下婴幼儿,以脓毒症及化脓性脑炎多见,对青霉素类抗生素大多耐药,青霉素不敏感株对其他多种抗生素的耐药性高于青霉素敏感株,万古霉素仍是治疗侵袭性SP病的首选药物,临床应根据侵袭性SP的耐药性分析合理使用抗生素。

关 键 词:链球菌,肺炎  儿童  抗药性  微生物敏感性试验

A clinical analysis of the drug resistance of the invasive Streptococcus Pneumoniae in Soochow district
Xiang Long,Xie Min-hui,Bai Zhen-jiang,Li Ying. A clinical analysis of the drug resistance of the invasive Streptococcus Pneumoniae in Soochow district[J]. Journal of Youjiang Medical College For Nationalities, 2011, 33(5): 617-620. DOI: 10.3969/j.issn.1001-5817.2011.05.006
Authors:Xiang Long  Xie Min-hui  Bai Zhen-jiang  Li Ying
Affiliation:Xiang Long,Xie Min-hui,Bai Zhen-jiang,Li Ying(Department of Pediatric Intensive Care Unit,Affiliated Children's Hospital ofSoochow University,Soochow,Jiangsu 215003,China )
Abstract:Objective To investigate the status quo and drug resistance of the invasive streptococcus pneumoniae(SP) infection in children from Soochow district for providing evidence of prevention and clinical treatment. Methods The records of 35 child patients(41 specimens) diagnosed with invasive streptococcus pneumonia infection were analyzed in this paper.We studied about their clinical characters and susceptibility test.According to drug resistance test results,the child patients were divided into two groups: the...
Keywords:Streptococcus pneumoniae  child  drug resistance  microbial sensitivity tests  
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