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The neuromuscular blocking activity of spectinomycin on the rat sciatic nerve-gastrocnemius muscle preparation |
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| Authors: | G Renna R Cagiano T Fiore V Cuomo |
| Abstract: | Spectinomycin displays a dose-dependent neuromuscular blocking activity in vivo. The neuromuscular blockade elicited by spectinomycin is potentiated by d-tubocurarine. Neostigmine methylsulfate is unable to reverse the neuromuscular blocking activity of spectinomycin, whereas calcium chloride counteracts the neuromuscular blockade induced by this antibiotic. |
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