| 刺五加叶皂甙对实验性非胰岛素依赖型大鼠心肌酶的影响 |
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| 引用本文： | 张义栋,孟德欣,邢德刚. 刺五加叶皂甙对实验性非胰岛素依赖型大鼠心肌酶的影响[J]. 黑龙江医药科学, 2001, 24(5): 10-11 |
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| 作者姓名： | 张义栋 孟德欣 邢德刚 |
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| 作者单位： | 佳木斯大学基础医学院生理教研室 |
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| 摘 要： | 目的：本实验通过观察不同剂量的刺五加叶皂甙对实验性NIDDM大鼠心肌LDH和ICDH的影响，对心肌病变治疗的机制作初步探讨。方法：Wistar大鼠，4－6月龄，造成NIDDM分别给予ASS100mg/Kg、200mg/Kg灌胃8周。结果：刺五叶皂甙能提高糖尿病大鼠心肌LDH、ICDH的活性，治疗组明显高于模型组（P＜0.01）。结论：刺五加叶皂甙可提高糖尿病大鼠心肌中的LDH和ICDH的活性，恢复心肌的正常能量代谢。
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| 关 键 词： | 非胰岛素依赖型糖尿病 刺五加叶皂甙 心肌 LDH ICDH |
| 修稿时间： | 2001-07-10 |
Effects of ASS on the activities of myocardial LDH and ICDH in NIDDM rats model |
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| MENG Dexin XING Degang,ZHANG Yidong. Effects of ASS on the activities of myocardial LDH and ICDH in NIDDM rats model[J]. Heilongjiang Medicine and Pharmacy, 2001, 24(5): 10-11 |
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| Authors: | MENG Dexin XING Degang ZHANG Yidong |
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| Abstract: | Objective: To observe the effects of different dosages of ASS on myocardial LDH and ICDH in experimental NIDDM rats and explore the therapy mechanism of the cardiomyopathy in NIDDM rats. Methods: Wister rats of 4 to 6-month age ,were poured with ASS 100mg/kg and 200mg/kg respectively into stomach for 8 weeks after they became NIDDM rats model. Results: ASS raised the activities of myocardial LDH and ICDH in NIDDM rats model. higher in treatment group than model group(P<0.01). Conclusion: ASS can raise the activities of myocardial LDH and ICDH in NIDDM rats model and recover myocardial normal energy metabolism. |
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| Keywords: | NIDDM myocardium ASS |
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