1629例中枢神经系统肿瘤的临床病理分析

目的 探讨中枢神经系统肿瘤的临床特点和病理类型,提高对中枢神经系统肿瘤进行病理诊断的准确性.方法 按2007年WHO中枢神经系统肿瘤的分类标准,对1 629例中枢神经系统肿瘤的临床及病理资料进行总结分析.结果 1629例肿瘤中,神经上皮组织肿瘤509例(占39.67%);脑神经和脊神经根肿瘤155例(占12.08%),脑膜肿瘤495例(占38.58%),淋巴瘤和造血组织肿瘤16例(占1.25%),生殖细胞肿瘤10例(占0.78%),颅咽管瘤35例(占2.73%),转移性肿瘤63例(占4.91%).成人组以脑膜瘤、高级别神经上皮组织肿瘤和神经鞘瘤为常见类型,而＜16岁儿童组则以髓母细胞瘤、低级别神经上皮肿瘤和毛细胞型星形细胞瘤常见.神经上皮组织肿瘤、胚胎性肿瘤和转移性肿瘤男性多于女性,脑膜瘤女性多于男性.1 629例肿瘤的发病部位以幕上1 234例(占75.75%)为主,幕下272例(占16.70%),椎管内123例(占7.55%).幕上主要以大脑半球的神经上皮组织肿瘤、脑膜瘤和鞍区的垂体腺瘤、颅咽管瘤为多见;幕下常见的肿瘤为小脑的血管母细胞瘤、髓母细胞瘤、毛细胞型星形细胞瘤和小脑桥脑角的神经鞘瘤、脑膜瘤;椎管内最多见的肿瘤为神经鞘瘤.结论 中枢神经系统肿瘤中,神经上皮肿瘤最多见,其次为脑膜肿瘤.肿瘤的组织病理学类型与患者的年龄、性别和肿瘤的部位等因素有关,了解其特点,对于正确的病理诊断有重要意义.

Clinicopathology of 1629 cases of central nervous system tumors

Objective] To investigate the clinical and pathological features of central nervous system tumors(CNS Tumors) and to improve the accuracy of pathological diagnosis.Methods] The clinical and pathological data of 1 629 cases of CNS tumors were collected and analyzed according to the 2007 WHO Classification of Tumors of CNS.Results] Among 1629 cases,in which 509 cases(39.67%) were intraepithelial tissue tumors,155 cases(12.08%) were cranial and vertebral nerve tumors,495 cases(38.58%) were meningeal tumors,...