| 脑缺血早期大脑皮质区神经元内一氧化氮合酶活性的变化 |
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| 引用本文： | 梅元武,孙秀,童萼塘. 脑缺血早期大脑皮质区神经元内一氧化氮合酶活性的变化[J]. 卒中与神经疾病, 1999, 6(1): 13-15 |
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| 作者姓名： | 梅元武 孙秀 童萼塘 |
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| 作者单位： | 武汉同济医科大学附属协和医院神经内科 |
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| 摘 要： | 建立大鼠ＭＣＡＯ局灶脑缺血模型，利用ＮＡＤＰＨ－ｄ组织化学方法检测脑缺血早期大脑皮质缺血区神经元内一氧化氮合酶活性的变化。结果显示脑缺血早期３０ｍｉｎ神经元内一氧化氮合酶活性开始至高峰，随后下降，脑缺血后６０ｍｉｎ，降至正常。
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| 关 键 词： | 脑缺血 一氧化氮合酶 大脑皮质 神经元 |
The changes of nitric oxide synthase activity in cortical neurons during early cerebral ischemic period |
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| Mei Yuanwu,Sun Xiu,Tong Etang. The changes of nitric oxide synthase activity in cortical neurons during early cerebral ischemic period[J]. Stroke and Nervous Diseases, 1999, 6(1): 13-15 |
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| Authors: | Mei Yuanwu Sun Xiu Tong Etang |
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| Affiliation: | Mei Yuanwu,Sun Xiu,Tong Etang. Department of Neurology,Xiehe Hospital Tongji Medical University,Wuhan 430022 |
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| Abstract: | In this study,we established rat models of middle ceretral artery occlusion,used NADPH d histochemical technique to investigate the activity of nitric oxide synthase in cortical neurons during early cerebral ischemic period.The results showed that its activity increased to the peak at 30min after ischemia and then decreased to normal line at 60 min after ischemia. |
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| Keywords: | Cerebral ischemia Nitric oxide synthase Nitric oxide |
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