20例口腔颌面部腺样囊性癌的临床病理分析

我科从1977～1991年经治口腔颌面部涎腺腺样囊性癌20例,大涎腺13例,小涎腺4例,其它3例。男性7例,女性13例.发病年龄27～70岁,平均年龄48岁。本组临床资料表明:涎腺腺样囊性癌易沿血管神经束和组织间隙扩散。筛状型预后最好,实体型预后最差。影响预后的主要因素有病人的性别、年龄、肿瘤部位、临床分期,组织学诊断,肿瘤分级以及最后一次手术切缘是否干净。辅助治疗可以改变这些影响预后的因素。

CLINICOPATHOIOGIC STUDY OF TWENTY CASES WITH ADENOID CYSTIC CARCINOMA IN THE ORAL AND MAXILLO-FACIAL REGIONS

From 1977 to 1991 twenty patients with adenoid cystic carcinoma of salivary gland in the oral and Maxillo-facial regions were treated by surgery in our department. Thirteen cases with adenoid cystic carcinoma originated in the major salivary gland and four cases originated in the minior salivary gland and three cases in the other position. The male and female patients were 7 and 13 respectively. The patient's ages ranged from. 27 to 70 years old, the average age was 48 years old. The present data showed that the biologic feature of this tumour was liable to spread along the vasculonerve-bundles and tissue spaces. The prognosis was best for the cribriform type and worst for the solid type. Factors influencing survival were patient's sex and age, tumor site, clinical stage, histologic diagnosis, tumor grade, and whether or not the final surgical margins were clear. Adjuvant therapy could affect these prognostic factors.