| 益心饮对病毒性心肌炎小鼠SOD及MDA活性的影响 |
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| 引用本文： | 郑培永,秦志丰,魏晓.益心饮对病毒性心肌炎小鼠SOD及MDA活性的影响[J].天津中医药,2004,21(3):185-187. |
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| 作者姓名： | 郑培永 秦志丰 魏晓 |
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| 作者单位： | 1. 上海中医药大学附属龙华医院,上海,200032
2. 第二军医大学长征医院,上海,200030 |
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| 基金项目： | 全军医药卫生科研基金课题 (01MA158) |
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| 摘 要： | 目的]观察益心饮对病毒性心肌炎小鼠超氧化物歧化酶 (SOD)及丙二醛 (MDA)活性的影响。方法]Balb/c小鼠120只均为雄性 ,体质量 (20±2)g ,随机分为6组 ,各组在给药后第7d和第14d分别处死8只及全部小鼠 ,眼眶取血制备血清 ,进行SOD和MDA检测。结果]与病毒对照组相比 ,益心饮中剂量组、大剂量组在第7d和第14d能显著提高血浆SOD活性 ,降低MDA含量 (P<0.01)。结论]益心饮能减轻氧自由基对心肌膜脂质过氧化损伤反应
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| 关 键 词： | 病毒性心肌炎 益心饮 超氧化物歧化酶（SOD） 丙二醛（MDA） |
| 文章编号： | 1672-1519(2004)03-0185-03 |
| 收稿时间： | 2004/1/13 0:00:00 |
| 修稿时间： | 2004年1月13日 |
Influence of Yi Xin Drink to SOD and MDA activity in mice with viral myocarditis |
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| ZHENG Pei-yong,QIN Zhi-feng and WEI Xiao.Influence of Yi Xin Drink to SOD and MDA activity in mice with viral myocarditis[J].Tianjin Journal of Traditional Chin Medicine,2004,21(3):185-187. |
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| Authors: | ZHENG Pei-yong QIN Zhi-feng and WEI Xiao |
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| Institution: | Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai, 300032, China |
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| Abstract: | Objective]To observe the influence of Yi Xin Drink to SOD and MDA activity in mice with viral myocarditis.Method]One hundred and twenty male Balb/c mice,weighing(20±2)g,were randomly divided into6groups,8 mice in each group were killed after 7d and 14d medication respectively.Serum was prepared from the orbit blood sampling for the SOD and MDA detection.Result]Comparing with virus control group,the Yi Xin Drink in middle dosage group,big dosage group could increase serum SOD activity at 7d and 14d evidently,decrease the MDA content(P<0.01).Conclusion]The Yi Xin Drink can alleviate lipid peroxidation damage reaction of myocardial membrane induced by oxy-gen-derived free radidicals. |
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| Keywords: | viral myocarditis Yi Xin Drink SOD MDA |
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