2型糖尿病患者血清F水平及Ins,FBG相关性探讨

目的 :探讨 2型糖尿病患者皮质醇水平的变化及其与血糖和胰岛素的相关性。方法 :测定 2 6例 2型糖尿病患者晨 8时的血糖、胰岛素及皮质醇水平。结果 :2型糖尿病患者血清皮质醇水平明显高于正常人 (P<0 0 1) ,且 2型糖尿病患者血皮质醇浓度与空腹血糖呈正相关 (r =0 .32 ,P <0 0 1) ,与胰岛素无直线相关性。结论 :2型糖尿病一定程度上存在皮质醇分泌的紊乱。

Serum Cortisol Level and its Correlation to Serum Insulin and Fasting Blood Sugar Levels in Patients with Type 2 Diabetes Mellitus

Objective To investigate the change of serum cortisol levels and its correlation to blood sugar and serum insulin levels in patients with type 2 diabetes mellitus. Methods Blood sugar with oxidase method and serum cortisol insulin levels with RIA (8 AM fasting specimen) were meusured in 26 patients with type 2 diabetes mellitus and 30 controls. Results The serum cortisol levels in the diabetic patients were significantly higher than those in the controls (P<0.01). The cortisol levels were positively correlated to the blood sugar levels (r=0.32, P<0.01), but not correlated to insulin levels. Conclusion There were cortisol secretion disturbances in patients with type 2 diabetes.