Recurrence of Wegener's granulomatosis 13 years after renal transplantation |
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| Institution: | 1. Unit for Environmental Sciences and Management (UESM), North-West University, Potchefstroom 2520, South Africa;2. Department of Botany, Institute for Coastal and Marine Research, Nelson Mandela University, Port Elizabeth 6031, South Africa;3. Johannesburg Business School (JBS), University of Johannesburg, Johannesburg 2092, South Africa;4. Nanogene and Drug Delivery Group, Department of Biochemistry, University of KwaZulu-Natal, Durban 4001, South Africa;5. School of Life Sciences, University of KwaZulu-Natal, Durban 4001, South Africa |
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| Abstract: | Wegener's granulomatosis (WG) can cause renal failure, requiring long-term renal replacement therapy. Renal transplantation in patients with WG is successful, but the risk for recurrence of the disease necessitates continued vigilance. We report a patient that originally presented with acute renal failure secondary to a pauci-immune focal necrotizing crescentic glomerulonephritis. Subsequent nasal involvement and serologic tests for antineutrophil cytoplasmic antibodies suggested a diagnosis of WG. © 2001 by the National Kidney Foundation, Inc. |
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| Keywords: | Wegener's granulomatosis vasculitis renal transplantation immunosuppression |
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