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甲硝唑、阿莫西林和兰索拉唑联合治疗幽门螺杆菌阳性消化性溃疡疗效观察
引用本文:龚兆元.甲硝唑、阿莫西林和兰索拉唑联合治疗幽门螺杆菌阳性消化性溃疡疗效观察[J].白求恩军医学院学报,2012,10(3):191-192.
作者姓名:龚兆元
作者单位:龚兆元 (湖南省张家界市第二人民医院内科,427300) ;
摘    要:目的观察甲硝唑、阿莫西林和兰索拉唑联合治疗幽门螺杆菌(Hp)阳性消化性溃疡的疗效。方法将84例Hp阳性消化性溃疡患者随机分为观察组和对照组,各42例。观察组给予甲硝唑、阿莫西林和兰索拉唑治疗,对照组给予甲硝唑、阿莫西林和雷尼替丁治疗;疗程均为28d。比较两组患者的疗效。结果观察组的治愈率及Hp根除率均高于对照组(P0.05)。结论甲硝唑、阿莫西林和兰索拉唑三联疗法治疗Hp阳性消化性溃疡疗效显著,值得在临床上推广。

关 键 词:甲硝唑  阿莫西林  兰索拉唑  幽门螺杆菌阳性消化性溃疡

Efficacy of treating Hp positive peptic ulcer with metronidazole,amoxicillin and lansoprazole
GONG Zhaoyuan.Efficacy of treating Hp positive peptic ulcer with metronidazole,amoxicillin and lansoprazole[J].Journal of Bethune Military Medical College,2012,10(3):191-192.
Authors:GONG Zhaoyuan
Institution:GONG Zhaoyuan.Department of Internal Medicine,the Second People’s Hospital of Zhangjiajie,Zhangjiajie,Hunan 427300,China
Abstract:Objective To observe the efficacy of treating Hp positive peptic ulcer with metronidazole,amoxicillin and lansoprazole.Methods 84 patients with Hp positive peptic ulcer patients were randomly divided into treatment group and control group.The patients in the treatment group were treated with the combined administration of metronidazole,amoxicillin,and lansoprazole,while the patients in the control group were treated with the combined administration of metronidazole,amoxicillin and ranitidine.The course of treatment lasted for 28 days.The efficacy of the patients in both groups were compared.Results The recovery rate and the Helicobacter pylori eradication rate of the patients in the treatment group were significantly higher than those of the control group(P<0.05).Conclusion Treating Hp positive peptic ulcer with metronidazole,amoxicillin and lansoprazole which has obvious efficacy and less adverse reaction is worth promoting in clinical practice.
Keywords:Metronidazole  Amoxicillin  Lansoprazole  Helicobacter pylori positive peptic ulcer
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