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| 多囊卵巢综合征患者胰岛素抵抗特征及相关因素研究 | |
| 引用本文： | 赵正云,沈冰珊,李小玲,谢裕达,黄威.多囊卵巢综合征患者胰岛素抵抗特征及相关因素研究[J].中国全科医学,2011,14(24). |
| 作者姓名： | 赵正云 沈冰珊 李小玲 谢裕达 黄威 |
| 作者单位： | 1. 广东省佛山市南海黄岐医院妇科,528248 2. 广东省佛山市南海黄岐医院检验科,528248 3. 广东省佛山市南海黄岐医院超声科,528248 |
| 摘 要： | 目的 探讨多囊卵巢综合征(PCOS)患者胰岛素抵抗(IR)特征及其相关因素.方法 对80例PCOS患者(其中肥胖49例,非肥胖31例)的临床特征及内分泌、糖代谢指标空腹血糖(FPG)、空腹胰岛素(FINS)等]进行回顾性分析.用稳态模型胰岛素抵抗指数(HOMA-IR)、空腹胰岛素敏感指数(ISI)评估胰岛素敏感性.结果 两组患者睾酮(T)、黄体生成素(LH)、卵泡刺激素(FSH)、LH/FSH比较,差异均无统计学意义(P＞0.05).肥胖PCOS组患者的FPG、FINS水平及HOMA-IR、ISI均显著高于非肥胖PCOS组,差异有统计学意义(P＜0.05).肥胖PCOS组和非肥胖PCOS组患者IR发生率分别为86%(42/49)和52%(16/31),差异有统计学意义(P＜0.05).结论 肥胖PCOS患者较非肥胖PCOS患者存在更严重的IR. |
| 关 键 词： | 多囊卵巢综合征 肥胖症 胰岛素抵抗 |
Insulin Resistance and Its Relative Factors in Polycystic Ovarian Syndrome |
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| ZHAO Zheng-yun,SHEN Bing-shan,LI Xiao-ling,et al..Insulin Resistance and Its Relative Factors in Polycystic Ovarian Syndrome[J].Chinese General Practice,2011,14(24). | |
| Authors: | ZHAO Zheng-yun SHEN Bing-shan LI Xiao-ling |
| Institution: | ZHAO Zheng-yun,SHEN Bing-shan,LI Xiao-ling,et al.Gynecology Department,Huangqi Hospital of Nanhai,Foshan 528248,China |
| Abstract: | Objective To explore the characteristics of insulin resistance(IR) and its relative factors in polycystic ovarian syndrome(PCOS).Methods Clinical characteristics,endocrinal markers,and glucose metabolism indices including fasting plasma glucose(FPG) and fasting plasma insulin(FINS) of 80 PCOS patients(49 obesity and 31 non-obesity) were retrospectively analyzed.Homeostasis model assessment-insulin resistance(HOMA-IR) and insulin sensitive index(ISI) were employed to assess insulin sensitivity.Results No sig... |
| Keywords: | Polycystic ovary syndrome Obesity Insulin resistance |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |