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| 联合血浆置换治疗对重型肝炎近期疗效的影响因素研究 | |
| 引用本文： | 刘浩,熊静平,孙静,鲁晓擘,肖琳,孙晓凤,李琴,邓泽润,张跃新.联合血浆置换治疗对重型肝炎近期疗效的影响因素研究[J].中国全科医学,2011,14(24). |
| 作者姓名： | 刘浩 熊静平 孙静 鲁晓擘 肖琳 孙晓凤 李琴 邓泽润 张跃新 |
| 作者单位： | 1. 新疆医科大学第一附属医院感染科,新疆乌鲁木齐市,830054 2. 新疆医科大学第二附属医院消化科 3. 和田市传染病医院 |
| 基金项目： | 国家"十一五"重大攻关课题项目 |
| 摘 要： | 目的 探讨联合血浆置换(PE)治疗对重型肝炎近期疗效的影响因素.方法 对128例重型肝炎患者在内科综合治疗的基础上行PE治疗,从发病年龄、置换次数、治疗间隔时间、临床分期、肝脏基础疾病、并发症及终末期肝病模型(MELD)评分等因素对PE治疗的疗效进行评价.结果 PE治疗有效80例,总有效率为62.5%,治疗前后血清胆红素、胆汁酸、清蛋白、凝血功能比较,差异均有统计学意义(P＜0.05).有效与无效患者的发病年龄、PE治疗次数、治疗间隔时间、肝脏基础疾病、临床分期、并发症、MELD评分、疗效比较,差异均有统计学意义(P＜0.05).结论 患者发病年龄、PE治疗次数、治疗间隔时间、肝脏基础疾病、临床分期、并发症的多少、MELD评分可作为判断PE治疗疗效的重要指标. |
| 关 键 词： | 血浆置换 肝炎 治疗结果 |
Influencing Factors for Short-Term Curative Effects of Joint Plasma Exchange Treatment on Fulminant Hepatitis |
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| LIU Hao,XIONG Jing-ping,SUN Jing,et al..Influencing Factors for Short-Term Curative Effects of Joint Plasma Exchange Treatment on Fulminant Hepatitis[J].Chinese General Practice,2011,14(24). | |
| Authors: | LIU Hao XIONG Jing-ping SUN Jing |
| Institution: | LIU Hao,XIONG Jing-ping,SUN Jing,et al.Department of Infectious Diseases,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China |
| Abstract: | Objective To explore the influencing factors for short-term curative effects of joint plasma exchange(PE) treatment on fulminant hepatitis.Methods A total of 128 patients with severe hepatitis underwent PE treatment in addition to comprehensive medical therapy.Factors including exchange times,age of onset,interval time,clinical stage,underlying liver diseases,complications,and MELD score and biochemical index of efficacy were analyzed.Results In total,80 patients survived(62.5%).Significant differences exis... |
| Keywords: | Plasma exchange Hepatitis Treatment outcome |
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