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rK39免疫层析试条诊断人体内脏利什曼病和感染犬
引用本文:张富南,张建国,张丽萍.rK39免疫层析试条诊断人体内脏利什曼病和感染犬[J].寄生虫病与感染性疾病,2011,9(4):181-184.
作者姓名:张富南  张建国  张丽萍
作者单位:1. 四川省疾病预防控制中心寄防所,四川 成都,610041
2. 四川大学华西基础医学与法医学院形态学实验室
摘    要:目的 评价rk39免疫层析试条对内脏利什曼病诊断和流行病学调查中的应用价值.方法 用rk39试条检测就诊者或临床医生考虑为黑热病的患者或进行过病原学检查的患者,并在黑热病疫区现场检测家犬.结果 用rk39试条检测具有流行病学史就诊者358人,黑热病抗体阳性244例,阳性检出率68.16%.接受rk39试条与病原学2种方法检查的207人中,均为阳性者131例,2者阳性符合率为100%;对单-显示rk39试条阳性71例,用锑剂治疗均治愈,证实均为黑热病.rk39试条检查疫区家犬443只,检出阳性犬43只,阳性率为9.71%,阳性犬以5岁以下犬龄多见.结论 与传统诊断内脏利什曼病方法相比较,rK39试条具有更快速、操作简便、敏感和特异性高以及低损伤性,可用于流行区的内脏利什曼病的诊断和筛选;rK39试条可在潜伏期中发现黑热病患者和无症状感染犬,对黑热病患者的诊断和感染犬的检出具有很高的价值.

关 键 词:rk39免疫层析试条  诊断  内脏利什曼病  无症状感染

RK39 Dipsticks in the Diagnosis of Human Visceral Leishmaniasis and Infected Dogs
ZHANG Fu-nan , ZHANG Jian-guo , ZHANG Li-ping.RK39 Dipsticks in the Diagnosis of Human Visceral Leishmaniasis and Infected Dogs[J].Parastoses and Infectious Diseases,2011,9(4):181-184.
Authors:ZHANG Fu-nan  ZHANG Jian-guo  ZHANG Li-ping
Institution:ZHANG Fu-nan1,ZHANG Jian-guo2,ZHANG Li-ping1 1 Institute of Parasitic Disease,Sichuan Center for Disease Control and Prevention,Chengdu 610041,Sichuan Province,China. 2 Morphology Laboratory,School of Preclinic and Forensic Medicine,Sichuan University,Chengdu 610207,China.
Abstract:Objective To evaluate the application of rk39 dipstick in the diagnosis of visceral leishmaniasis and the epidemiological investigation.Methods Patients who were considered to be Kala-azar by clinic doctors or those with etiological examinations were given rk39 dipsticks detection,and also the dogs in leishmaniasis epidemic areas were detected.Results Among the 358 cases with epidemic history,244 of them were antibody positive.The positive rate was 68.16%.Among the 207 cases who received both rk39 dipstick ...
Keywords:rk39 dipstick  diagnosis  visceral leishmaniasis  asymptomatic infection  
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