人工关节置换后中医药治疗下肢深静脉血栓形成

背景：人工关节置换后下肢深静脉血栓形成的发病率较高,主要原因包括血管内膜受损、血流速度缓慢及血液呈高凝状态3个方面。目的：评价中医药在防治人工关节置换后下肢深静脉血栓形成中的作用。方法：以＂中医药,下肢深静脉血栓形成,防治,人工关节置换＂为关键词,采用计算机检索1989-01/2011-10相关文章。纳入与中医药防治下肢深静脉血栓形成相关的文章;排除重复研究或Meta分析类文章。共纳入26篇相关文献进行综述。结果与结论：下肢深静脉血栓形成目前主要的治疗方法包括功能锻炼、梯度压力治疗、溶栓及抗凝药物治疗等。近年中医药在治疗下肢深静脉血栓形成中显示了良好的功效,主要包括丹参、川芎嗪、黄芪等,一些具有活血化瘀的中药复方也具有防治下肢深静脉血栓形成的作用,且与低分子量肝素联合治疗可起到更好的效果。说明中医药无论是在预防下肢深静脉血栓形成还是在其治疗中都显示出良好的效果,且不良反应较小,中西医结合功能锻炼将是防治下肢深静脉血栓形成的有效手段。

Chinese medicine treatment of deep venous thrombosis of the lower extremity after artificial joint replacement

BACKGROUND：The incidence of lower extremity deep venous thrombosis is high after artificial joint replacement and mainly caused by intimal damage,slow blood flow velocity and blood hypercoagulable state.OBJECTIVE：To evaluate the preventive and therapeutic effects of Chinese medicine on the lower extremity deep venous thrombosis after artificial joint replacement.METHODS：A computer-based online search was performed for the articles from January 1989 to October 2011 with the kewords of ＂Chinese medicine,lower extremity deep venous thrombosis,prevention and treatment,artificial joint replacement＂.The articles that related with the Chinese medicine for the treatment of lower extremity deep venous thrombosis after artificial joint replacement were included;the repeat studies or Meta-analysis articles were excluded.A total of 26 articles were included to review.RESULTS AND CONCLUSION：For the treatment of lower extremity deep venous thrombosis,the main treatment methods include functional exercise,the pressure gradient therapy,and the thrombolytic and anticoagulant therapy.In recent years,the Chinese medicine shows a good effect in the treatment of lower extremity deep venous thrombosis and the main Chinese medicine include salvia miltiorrhiza,ligustrazine and astragalus mongholicus.Some Chinese herbal compound with the effect of promoting blood circulation also has a role in the prevention of lower extremity deep venous thrombosis.It demonstrates that Chinese medicine shows a good effect both on the prevention and treatment of lower extremity deep venous thrombosis with less adverse reaction.Chinese and Western medicine combined with functional exercise is an effective means for the prevention and treatment of lower extremity deep venous thrombosis.